This report contains our most up-to-date research.

To view or print the full report click here: Adhesive Arachnoiditis Report 2020


Adhesive arachnoiditis (AA) is an inflammatory disease of the lower spinal canal that involves cauda equina nerve roots and the arachnoid-dural covering (meninges) of the spinal canal. While once a rare disease, it is now emerging in every community. Diagnostic and treatment protocols have been developed and are presented here. A clinical profile of 80 MRI-confirmed cases show that AA is primarily a disease of mid to late-age females. The most common underlying cause is a structural disorder of the spine. Genetic connective tissue/collagen disorders of the Ehlers-Danlos Syndrome type appear to be the second most common cause of AA. Multiple surgeries and spinal interventions were common in these cases. A symptom profile of AA is quite uniform and includes pain relief on change of position, jerks or tremors in the legs, urinary dysfunction, and sensations of insects crawling or water dripping on the skin. Treatment specifically directed at suppressing neuroinflammation, promoting tissue regeneration, and providing aggressive pain management Is the most successful approach for halting the progression of the disease, restoring function, and enhancing patient quality of life.